Optimization and characterization of novel sustained ...
1. Introduction. Dexibuprofen is the S (+)-isomer of ibuprofen that was launched in Austria in 1994 [].Numerous studies have shown that the S (+) ibuprofen is more effective against analgesic and anti-inflammatory effects and in reducing acute gastric damage than its racemate [2,3].The activity of dexibuprofen is 160 and 1.6 times of its left-handed and racemic forms [,,, ].